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Subjects affected by Type I Diabetes (T1D) are constantly confronted with the complicated problem of administering themselves an adequate amount of insulin, so as to keep their blood-glucose concentration in a nearly physiological range. Recently, powerful technological tools have been developed to better face this challenge, in particular the so-called Artificial Pancreas (AP). Unluckily, the AP actuator, an insulin pump, is subject to faults, with potential serious consequences for subjects' safety. This calls for the development of advanced fault detection (FD) methods, leveraging the unprecedented data availability in this application. In this paper we tackle the problem of detecting insulin pump malfunctioning using a model-free approach, so that the complex sub-task of identifying a model of patients physiology is avoided. Moreover, we employed unsupervised methods since labeled data are hardly available in practice. The adopted data-driven Anomaly Detection (AD) methods are Local Outlier Factor and Connectivity-based Outlier Factor. The methods are applied on a feature set able to account for the physiological dynamics of T1D patients. The proposed algorithms are tested on a synthetic dataset, generated using the “UVA/Padova Type 1 Diabetic Simulator”, an accurate nonlinear computer simulator of the T1D subject physiology. Both methods show precision ~75% and recall ~60%• The described approach is suitable both for embedding in medical devices, such as the AP, and implementation in cloud-based remote monitoring systems.

The diffusion in Power Systems of distributed renewable energy resources, electric vehicles and controllable loads has made advanced monitoring systems fundamental to cope with the consequent disturbances in power flows; advanced monitoring systems can be employed for Anomaly Detection, Root Cause Analysis and Control purposes.

Several Machine Learning-based approaches have been developed in the past recent years to detect if a power system is running under anomalous conditions and, eventually, to classify such situation with respect to known problems.

One of the aspects that makes Power Systems challenging to be tackled, is that the monitoring has to be performed on streams of data that have a time series evolution; this issue is generally tackled by performing a features extraction procedure before the classication phase. The features extraction phase consists of translating the informative content of time series data into scalar quantities: such procedure may be a time-consuming step that requires the involvement of process experts to avoid loss of information in the making; moreover, extracted features designed to capture certain behaviors of the system, may not be informative under unseen conditions leading to poor monitoring performances.

A different type of data-driven approaches, that will be reviewed in this chapter, allow to perform classication directly on the raw time series data, avoiding the features extraction phase: among these approaches, Dynamic Time Warping and Symbolic-based methodologies have been widely applied in many application areas.

In the following, pros and cons of each approach will be discussed and practical implementation guidelines will be provided.

In the context of activity recognition, wearable devices arenowadays the preferable hardware thanks to their usability, user expe-rience and performances; at the same time, these devices present limi-tations in terms of computational capability and memory, which forcethe algorithm design to be at the same time ecient and simple. Inthis work, we adopt Symbolic Aggregate Approximation (SAX), a sym-bolic approach for information retrieval in time series data that allowsdimensionality and numerosity reduction; SAX is employed here, in com-bination with 1-Nearest Neighbor classier, to identify activity phases incontinuous repetitive activities from inertial time-series data. The pro-posed approach is validated on a public activity recognition dataset.

In many applications, and especially thosewhere batch processes are involved, a target scalar outputof interest is often dependent on one or more time seriesof data. With the exponential growth in data logging inmodern industries such time series are increasingly availablefor statistical modeling in soft sensing applications. In orderto exploit time series data for predictive modelling, it isnecessary to summarise the information they contain as aset of features to use as model regressors. Typically thisis done in an unsupervised fashion using simple techniquessuch as computing statistical moments, principalcomponents or wavelet decompositions, often leading tosignificant information loss and hence suboptimal predictivemodels. In this paper, a functional learning paradigm isexploited in a supervised fashion to derive continuous,smooth estimates of time series data (yielding aggregatedlocal information), while simultaneously estimating a continuousshape function yielding optimal predictions. Theproposed Supervised Aggregative Feature Extraction (SAFE)methodology can be extended to support nonlinear predictivemodels by embedding the functional learning framework ina Reproducing Kernel Hilbert Spaces setting. SAFE has anumber of attractive features including closed form solutionand the ability to explicitly incorporate first and secondorder derivative information. Using simulation studies and apractical semiconductor manufacturing case study we highlightthe strengths of the new methodology with respect tostandard unsupervised feature extraction approaches.